BIOCHIPS: Lab-on-a-chip and DNA chips, new tools for high throughput genetic analysis and diagnostics.
Identifieur interne : 000244 ( France/Analysis ); précédent : 000243; suivant : 000245BIOCHIPS: Lab-on-a-chip and DNA chips, new tools for high throughput genetic analysis and diagnostics.
Auteurs : Marc Cuzin [France] ; Alexandra Fuchs ; Patrice Caillat ; Yves FouilletSource :
Abstract
Abstract: DNA chips, also known as DNA arrays, microarrays or oligochips, are miniaturized microsystems based on the ability of DNA to spontaneously find and bind its complementary sequence in a highly specific and reversible manner, known as hybridization. Thus, labeled DNA molecules in a sample are analyzed by DNA probes tethered at distinct sites on a solid support. The composition of the DNA sample is then deduced by analyzing the signal generated by labels present at each probe site.
Url:
DOI: 10.1007/978-3-642-56763-6_53
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: DNA chips, also known as DNA arrays, microarrays or oligochips, are miniaturized microsystems based on the ability of DNA to spontaneously find and bind its complementary sequence in a highly specific and reversible manner, known as hybridization. Thus, labeled DNA molecules in a sample are analyzed by DNA probes tethered at distinct sites on a solid support. The composition of the DNA sample is then deduced by analyzing the signal generated by labels present at each probe site.</div>
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